SELANK
Selank is a synthetic heptapeptide based on the naturally occurring tuftsin sequence. Human research has evaluated intranasal Selank in adults with generalized anxiety disorder, neurasthenia, and in acute neuroimaging experiments. The calculations below use the entire 10 mg vial and keep published study protocols separate from worked preparation examples.
Reconstitution Steps
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Protocol Overview
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Dosing Protocol
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Storage Instructions
Registered 0.15% product: Protected from light, stored at no more than 10 degrees C, and not frozen[5].
Opened registered product: The manufacturer permits storage at no more than 25 degrees C for up to 15 days[5].
Custom research preparation: Use formulation-specific stability and microbiological controls rather than transferring the finished-product shelf life.
Labeling: Record preparation date, final volume, concentration, vehicle, and storage conditions.
Important Notes
Small measurement and device details can materially change the amount delivered per spray.
Use a measured final volume, not the bottle capacity mark alone.
Verify that the actuator releases 0.10 mL per full stroke before applying the main table.
Prime and reprime exactly as specified for the pump, then record those actuations.
Keep the bottle upright and use a complete, consistent stroke for each recorded spray.
Treat the theoretical 50 or 100 sprays as nominal counts because priming and residual hold-up consume part of the volume.
A 10 mg vial contains 10,000 mcg total. Calculate the complete peptide requirement before modeling any multi-day published protocol.
Use a validated laboratory handling and stability plan for any custom multidose preparation.
How This Works
What Is Selank?
Selank is a synthetic peptide made of seven amino acids, developed in Russia. It’s based on tuftsin, a natural peptide your immune system already produces. Researchers added three extra amino acids to the end so it lasts longer in the body before getting broken down.
How It Works
Selank doesn’t just target one system. It hits several:
GABA receptors – modulates the same receptor family as anti-anxiety drugs, but without the sedation, brain fog, or dependence seen with benzos
Serotonin – stabilizes serotonin levels and its metabolites in the brain
Dopamine and norepinephrine – influences turnover of both in key brain regions
BDNF – boosts production of brain-derived neurotrophic factor, a protein tied to learning, memory, and neuron health
Enkephalins – blocks the enzymes that break down your body’s natural painkillers, raising their levels
Immune function – affects 50+ genes related to inflammation and immune response through its tuftsin backbone
Why Researchers Care
Anxiolytic effects without sedation or cognitive impairment
No tolerance or withdrawal in preclinical studies
Actually appears to sharpen cognition rather than dull it
Dual action as both a nootropic and anxiolytic is a rare combo
Broad gene expression changes (36 genes in the hippocampus within one hour)
Potential Benefits & Side Effects
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Lifestyle Factors
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Injection Technique
General subcutaneous guidance from clinical best-practice resources.
Clean your hands and work on a clean surface.
Swab the vial’s rubber stopper and injection site with alcohol; allow to dry.
Draw the calculated dose into the insulin syringe, eliminating air bubbles.
Suitable SC injection areas include the abdomen (2 inches from navel), outer thighs, upper outer arms, or flank/hip area.
Pinch a fold of skin between thumb and forefinger; insert the needle at 45–90° into subcutaneous tissue.
Do not aspirate for subcutaneous injections; inject slowly and steadily.
After injection, release the pinched skin and withdraw the needle at the same angle.
Apply gentle pressure with a clean cotton or alcohol pad; do not rub vigorously.
Rotate sites systematically with each dose to prevent irritation or tissue damage.
Immediately dispose of the used syringe in a proper sharps container.
